Methods: We analyzed and compared the concentration of cf-DNA in 174 SZ patients and 100 matched healthy controls by using quantitative real-time PCR by amplifying the Alu repeats. Therefore, we intend to explore whether cf-DNA levels are related to the occurrence and development of schizophrenia. However, the pathogenesis of schizophrenia remains unclear and there are no specific biomarkers. 5Center of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, Chinaīackground: Schizophrenia is a severe mental disorder, which has a major impact on the quality of life and imposes a huge burden on the family.4School of Public Health, Nantong University, Nantong, China.3Neurology Laboratory, Affiliated Hospital of Nantong University, Nantong, China.
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